Although I’ve consistently argued that you don’t need to train to
failure to maximize hypertrophy, findings like those observed in the
present meta-analysis (and plenty of practical experience) still lead me
to believe that training to failure may be more advisable than
the scientific literature would suggest. In a vacuum, it looks like a
fool’s bargain: training to failure probably doesn’t lead to more growth
on a per-set basis than stopping 2-3 reps shy of failure, but it causes
more fatigue, and comes with a higher recovery burden. But, training
to failure does have one major thing going for it: training to
failure ensures you are putting enough effort into each set to attain a
robust hypertrophy stimulus.